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In vitro diagnostic · Seminal oxidative stress

Male Infertility
Oxidative System

Rapid, objective oxidative-stress testing.

The MiOXSYS System

An objective measure of seminal oxidative stress

MiOXSYS measures oxidation-reduction potential (ORP) in semen — the balance between oxidants and antioxidants in seminal fluid. It surfaces a contributor to male infertility that a standard semen analysis does not directly assess.

~40%
of male infertility is linked to oxidative stress
<3min
galvanostatic measurement per sample
30µL
of raw semen — no sample preparation
1
single-use sensor strip per test
The MiOXSYS System — analyser, single-use sensor strips, sensor boxes and calibration kit
The system

MiOXSYS® Analyser & sensor strips

A benchtop analyser and single-use sensors that turn 30 µL of raw semen into an objective sORP reading — at the bench, in minutes.

Objective sORP value, normalised to sperm concentration
No centrifugation or reagent prep — raw sample straight onto the strip
One single-use strip per test, result in under three minutes
CE 0197FDAISO 13485GMP
The challenge

Male infertility
challenge

Infertility affects an estimated 15% of couples and, as defined by the World Health Organization, is the failure to achieve pregnancy after 12 months of regular unprotected intercourse. A male factor plays a role in up to half of these couples.

Many male infertility cases are diagnosed as idiopathic — no identifiable cause — leaving couples and clinicians without a clear path. Measuring oxidative stress helps address that gap.

Causes of male infertility
Causes of male infertility

What sits behind a male factor

Where male-factor infertility originates — and why so much of it stays unexplained. Distribution reported in the published andrology literature.

Unknown causes40–50%1
Gonad disorder30–40%1
Sperm transport disorder10–20%1
Hypothalamic-pituitary disorders1–2%1
Why ORP

The measure a routine analysis can miss

Oxidative stress, quantified

Excess reactive oxygen species can damage the sperm membrane and DNA. ORP measures that imbalance as a single number.

Insight beyond the basics

Useful in cases of unexplained or idiopathic infertility, where standard parameters appear within range.

A baseline to act on

A measurable starting point that can be re-tested to track change over a lifestyle or treatment course.

How it works

A result in three steps

Step 01
Apply the sample

Pipette 30 µL of raw, liquefied semen onto the single-use sensor strip — no centrifugation or preparation.

Step 02
Insert the sensor

Connect the strip to the analyser, which runs a galvanostatic measurement of the sample.

Step 03
Read the ORP value

In under three minutes the device displays the static ORP (sORP), normalised to sperm concentration.

Who it's for

Built for the teams investigating male-factor infertility

MiOXSYS is an in vitro diagnostic for trained professionals — a fast, objective ORP reading that sits alongside a standard semen analysis.

Fertility clinics

Add an objective, repeatable measure of oxidative stress when investigating unexplained or idiopathic infertility.

Andrology laboratories

Run ORP testing beside routine semen analysis — 30 µL of raw sample, one strip, no preparation step.

Clinicians & specialists

Establish a baseline sORP value to guide lifestyle or treatment decisions, then re-test to track change.

Specifications

The technical detail

SystemMiOXSYS® (Male Infertility Oxidative System)
MeasuresStatic oxidation-reduction potential (sORP)
MethodGalvanostatic measurement
Sample30 µL raw, liquefied semen
Test timeUnder 3 minutes
ConsumableSingle-use sensor strip
Result unitmV per 10⁶ sperm/ml
UseIn vitro diagnostic, by trained professionals
FAQ

Common questions

What is ORP, and why does it matter?
Oxidation-reduction potential reflects the balance between oxidants (reactive oxygen species) and antioxidants in seminal fluid. When oxidants dominate, the resulting oxidative stress can impair sperm function — something a standard semen analysis does not directly measure.
How is MiOXSYS different from a semen analysis?
A semen analysis reports count, motility and morphology. MiOXSYS adds a measure of oxidative stress, which can be relevant even when those standard parameters appear normal — particularly in unexplained infertility.
How much sample is needed?
Just 30 µL of raw, liquefied semen applied to a single-use sensor strip — no centrifugation or sample preparation, with a result in under three minutes.
Who is it for?
Fertility clinics and andrology laboratories investigating male-factor and unexplained infertility who want an objective, repeatable measure of seminal oxidative stress. It is an in vitro diagnostic for use by trained professionals.
For patients & couples Read the plain-language guide
Request

Request a MiOXSYS® System

Want to learn more about the MiOXSYS System and seminal oxidative-stress testing?

Contact for a quote today
References

1. World Health Organization. WHO laboratory manual for the examination and processing of human semen, 6th ed.

2. Agarwal A, et al. Oxidation-reduction potential as a new marker for oxidative stress: correlation to male infertility. Investigative urology / andrology literature.